Tissue Tranglutaminase Test - IgA

This test is used to find out the tissue transglutaminase antibodies-IgA in the blood. The Tissue Transglutaminase IgA Test is a diagnostic blood test for Coeliac disease. Coeliac disease is an autoimmune disorder that primarily affects your gut. Autoimmune disorders are diseases where your body attacks itself. Tissue transglutaminase is an enzyme that helps fix all the damage in your body. People who have coeliac disease often make antibodies that attack the tissue transglutaminase enzyme. They are known as anti-tTG antibodies. People with coeliac disease have issues with their small intestine and complain of diarrhoea, bloating, gaseous distension, anaemia and growth issues. Coeliac disease is triggered by gluten. Gluten is a protein found in grains like wheat, rye and barley. If you have coeliac disease, consuming gluten may be harmful to your health. Coeliac disease can lead to certain complications like malnutrition, osteoporosis, infertility and cancer of the intestine. Since the coeliac disease is an autoimmune disorder, it may also cause other autoimmune disorders like thyroid disease, type 1 diabetes, systemic lupus erythematosus, rheumatoid arthritis, Sjogren’s syndrome and autoimmune liver disorders. The Tissue Transglutaminase IgA Test is one of the multiple tests used to diagnose coeliac disease and to monitor the prognosis of the disease along with its treatment. The Tissue Transglutaminase IgA Test measures the presence of IgA antibodies against gluten in your blood. People with coeliac disease are allergic to gluten and IgA antibodies are formed as a result of the body’s immune response against tissue transglutaminase. Studies show that 1 in every 96 individuals suffer from coeliac disease in India. It is a far more common problem than is recognised in India. Research states that the Tissue Transglutaminase IgA Test is used for the diagnosis of coeliac disease with high specificity and sensitivity that is well suited for use in tropical countries like India