Fibrinogen Test

Fibrinogen is a soluble protein in the plasma that is broken down to fibrin by the enzyme thrombin to form clots. Fibrinogen is a protein that forms fibrin when acted upon by thrombin (an enzyme). In this process, a “fibrin clot” is formed. Fibrinogen is formed in the liver. The fibrinogen test is done whenever there is a deficiency of fibrinogen or factor I. This may be due to a number of reasons. The test involves the measurement of values of the clotting factor present in the blood. This test is done by the measurement of fibrinogen activity. The method used is known as the Clauss Method. It determines the fibrin polymerization function. The rate of formation of the blood clot is measured in this test. It measures the ability of fibrinogen to produce a fibrin clot. This test is basically a fibrinogen assay, which means that it is quantitative in nature. The clotting ability of the given blood sample is compared with standard or known values of clotting time, which forms the functional assay.